The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 20, 2014

Filed:

Feb. 27, 2009
Applicants:

Michael Mannion, Montreal, CA;

Stéphane Raeppel, St-Lazare, CA;

Stephen William Claridge, Montreal, CA;

Frédéric Gaudette, Sherbrooke, CA;

Lijie Zhan, Montreal, CA;

Ljubomir Isakovic, La Jolla, CA (US);

Oscar Mario Saavedra, Montreal, CA;

Tetsuyuki Uno, Okayama, JP;

Masashi Kishida, Ako, JP;

Arkadii Vaisburg, Kirkland, CA;

Inventors:

Michael Mannion, Montreal, CA;

Stéphane Raeppel, St-Lazare, CA;

Stephen William Claridge, Montreal, CA;

Frédéric Gaudette, Sherbrooke, CA;

Lijie Zhan, Montreal, CA;

Ljubomir Isakovic, La Jolla, CA (US);

Oscar Mario Saavedra, Montreal, CA;

Tetsuyuki Uno, Okayama, JP;

Masashi Kishida, Ako, JP;

Arkadii Vaisburg, Kirkland, CA;

Assignee:

MethylGene Inc., Montreal, CA;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/4365 (2006.01); C07D 513/04 (2006.01);
U.S. Cl.
CPC ...
Abstract

This invention relates to compounds that inhibit protein tyrosine kinase activity. In particular the invention relates to compounds that inhibit the protein tyrosine kinase activity of growth factor receptors, resulting in the inhibition of receptor signaling, for example, the inhibition of VEGF receptor signaling. The invention also provides compounds, compositions and methods for treating cell proliferative diseases and conditions and opthalmological diseases, disorders and conditions.


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