The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 20, 2014
Filed:
Dec. 06, 2012
Applicant:
Suppremol Gmbh, Martinsried, DE;
Inventors:
Phillip Mark Hogarth, Victoria, AU;
Bruce David Wines, Victoria, AU;
Assignee:
Trillium Therapeutics, Inc., Martinsried, DE;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 21/04 (2006.01); C07K 14/735 (2006.01);
U.S. Cl.
CPC ...
C07K 14/70535 (2013.01); C07K 2319/00 (2013.01); C07K 2319/30 (2013.01); C07K 2319/35 (2013.01); C07K 2319/70 (2013.01); C07K 2319/74 (2013.01); Y10S 530/868 (2013.01);
Abstract
A soluble multimeric protein or polypeptide is disclosed that is able to inhibit interaction of leukocyte Fcγ receptors (FcγR) and immunoglobulin G (IgG). The protein or polypeptide comprises two or more linked Fc binding regions, at least one of which is derived from an FcγR type receptor and, particularly, FcγRIIa. Also described are polynucleotide molecules encoding the protein or polypeptide and the use thereof in methods of treating a subject for an immune-complex (IC)-mediated inflammatory disease.