The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 20, 2014
Filed:
Mar. 17, 2011
Hanbin Shan, Gaoan, CN;
Zhedong Yuan, Shanghai, CN;
Xueyan Zhu, Shanghai, CN;
Peng Zhang, Pudong New Area, CN;
Hongjuan Pan, Shanghai, CN;
Xiong Yu, Hongkou, CN;
Hanbin Shan, Gaoan, CN;
Zhedong Yuan, Shanghai, CN;
Xueyan Zhu, Shanghai, CN;
Peng Zhang, Pudong New Area, CN;
Hongjuan Pan, Shanghai, CN;
Xiong Yu, Hongkou, CN;
Les Laboratoires Servier, Suresnes Cedex, FR;
Abstract
The present invention relates to an agomelatine hydrobromide hydrate of formula I wherein X is Br, preparation and use thereof, and to pharmaceutical compositions containing it. The agomelatine hydrobromide hydrate obtained through the present method has significant increased solubility than agomelatine, and therefore is more suitable for manufacturing pharmaceutical formulations. In addition, the product enjoys higher stability and purity. Using the present method, product of high purity can be obtained through a simple process, free of any complicated steps.