The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 20, 2014

Filed:

Apr. 22, 2009
Applicants:

Shuibing Chen, Arlington, MA (US);

Douglas A. Melton, Lexington, MA (US);

Malgorzata Borowiak, Somerville, MA (US);

Julia Lamenzo, Arlington, MA (US);

Stuart L. Schreiber, Boston, MA (US);

Lee F. Peng, Somerville, MA (US);

Lance Davidow, Lexington, MA (US);

Kelvin Lam, Arlington, MA (US);

Lee L. Rubin, Wellesley, MA (US);

Inventors:

Shuibing Chen, Arlington, MA (US);

Douglas A. Melton, Lexington, MA (US);

Malgorzata Borowiak, Somerville, MA (US);

Julia Lamenzo, Arlington, MA (US);

Stuart L. Schreiber, Boston, MA (US);

Lee F. Peng, Somerville, MA (US);

Lance Davidow, Lexington, MA (US);

Kelvin Lam, Arlington, MA (US);

Lee L. Rubin, Wellesley, MA (US);

Assignees:
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 5/00 (2006.01); C12N 5/071 (2010.01); C12N 5/02 (2006.01);
U.S. Cl.
CPC ...
Abstract

Certain embodiments disclosed herein are directed to a method of producing pancreatic cells or pancreatic cell precursors by exposing human embryonic stem cells to an effective amount of at least one compound listed in Table I to differentiate the human embryonic stem cells into the pancreatic cells or the pancreatic cell precursors. Kits and pancreatic cell lines produced using the methods are also described.


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