The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 20, 2014
Filed:
Aug. 26, 2005
Zhentao Liu, Hebei Province, CN;
Liying Yang, Hebei Province, CN;
Hanyu Yang, Hebei Province, CN;
Yuqing Gao, Hebei Province, CN;
Dongmin Shen, Hebei Province, CN;
Wenmin Guo, Heibei Province, CN;
Xiaolong Feng, Heibei Province, CN;
Jia Zheng, Heibei Province, CN;
Zhentao Liu, Hebei Province, CN;
Liying Yang, Hebei Province, CN;
Hanyu Yang, Hebei Province, CN;
Yuqing Gao, Hebei Province, CN;
Dongmin Shen, Hebei Province, CN;
Wenmin Guo, Heibei Province, CN;
Xiaolong Feng, Heibei Province, CN;
Jia Zheng, Heibei Province, CN;
CSPC ZhongQi Pharmaceutical Technology (Shijiazhuang) Co., Ltd, Shijiazhuang, Hebei, CN;
Abstract
The present invention relates to a novel drug delivery and release system, i.e. Self-emulsifying Drug Delivery System (SEDDS), of butylphthalide, to a preparation process thereof, and to a use thereof in a pharmaceutical formulation. The drug delivery system comprises as essential ingredients 1% to 65% of butylphthalide and 10% to 65% of a emulsifying agent, together with various excipients as required depending on the desired dosage forms. The present invention significantly increases the contact area between butylphthalide and the mucous membrane of the gastrointestinal tract, and therefore improves the absorptivity of the drug.