The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 20, 2014
Filed:
Apr. 29, 2010
Nathaniel Catron, Vernon Hills, IL (US);
Michael G. Fickes, Evanston, IL (US);
Cristina M. Fischer, Wadsworth, IL (US);
Anthony R. Haight, Wadsworth, IL (US);
Katherine Heemstra, Chicago, IL (US);
Yeshwant D. Sanzgiri, Gurnee, IL (US);
Eric A. Schmitt, Libertyville, IL (US);
Ping Tong, Libertyville, IL (US);
Geoff G. Z. Zhang, Libertyville, IL (US);
Deliang Zhou, Vernon Hills, IL (US);
Nathaniel Catron, Vernon Hills, IL (US);
Michael G. Fickes, Evanston, IL (US);
Cristina M. Fischer, Wadsworth, IL (US);
Anthony R. Haight, Wadsworth, IL (US);
Katherine Heemstra, Chicago, IL (US);
Yeshwant D. Sanzgiri, Gurnee, IL (US);
Eric A. Schmitt, Libertyville, IL (US);
Ping Tong, Libertyville, IL (US);
Geoff G. Z. Zhang, Libertyville, IL (US);
Deliang Zhou, Vernon Hills, IL (US);
AbbVie Inc., North Chicago, IL (US);
Abstract
An orally deliverable pharmaceutical composition comprises a Bcl-2 family protein inhibitory compound, e.g., ABT-263, a heavier-chalcogen antioxidant and a substantially non-aqueous lipid carrier, wherein said compound and said antioxidant are in solution in the carrier. The composition is suitable for oral administration to a subject in need thereof for treatment of a disease characterized by overexpression of one or more anti-apoptotic Bcl-2 family proteins, for example cancer.