The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 20, 2014
Filed:
Apr. 22, 2009
Mark Stephen Baird, Gwynedd, GB;
Juma' a Raheem Najeem Al-dulayymi, Gwynedd, GB;
Cornelia Theunissen, Gwynedd, GB;
Gani Koza, Gwynedd, GB;
Seppe Vander Beken, Ghent, BE;
Johan Adriaan Marc Grooten, Ghent, BE;
Mark Stephen Baird, Gwynedd, GB;
Juma' a Raheem Najeem Al-Dulayymi, Gwynedd, GB;
Cornelia Theunissen, Gwynedd, GB;
Gani Koza, Gwynedd, GB;
Seppe Vander Beken, Ghent, BE;
Johan Adriaan Marc Grooten, Ghent, BE;
Bangor University, Gwynedd, GB;
Universiteit Gent, Ghent, BE;
Abstract
A compound of formula (I) for use as an adjuvant in vaccination; wherein R is an optionally-substituted alkyl, alkenyl, alkynyl, aryl, arylalkyl or alkylaryl moiety having from 1 to 50 carbon atoms; Ris an optionally-substituted alkyl, alkenyl, alkynyl, aryl, arylalkyl or alkylaryl moiety having from 1 to 40 carbon atoms; each of R, Rand Ris independently selected from an optionally-substituted alkylene, alkenylene, alkynylene, arylene, arylalkylene or alkylarylene moiety having from 1 to 40 carbon atoms; each of X, Y and Z is independently selected from an optionally-substituted alkylene, alkenylene, alkynylene, arylene, alkylarylene or cycloalkylene, ketone, ester, amide, imide, imine, thioether, ether, thioester, thioketone; and P is selected from hydrogen, an alkyl group, a sugar residue, or a metal, phosphonium or ammonium species; wherein at least one of X, Y and Z includes a moiety selected from cyclopropyl, C=A, C-AH and C—OR; wherein Ris alkyl or haloalkyl, and A is S, O or NR, wherein Rmaybe H or 20 alkyl.