The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 20, 2014
Filed:
Jul. 14, 2010
Xiaohui Zhang, Westmont, IL (US);
David L. Kaplan, Concord, MA (US);
Scott E. Wharram, Pepperell, MA (US);
Stephen Mccarthy, Tyngsboro, MA (US);
Xiaohui Zhang, Westmont, IL (US);
David L. Kaplan, Concord, MA (US);
Scott E. Wharram, Pepperell, MA (US);
Stephen McCarthy, Tyngsboro, MA (US);
Trustees of Tufts College, Medford, MA (US);
Abstract
The present invention relates to the processes of preparing silkfibroin/polyethylene oxide blended materials, and the resulting materials thereof, which are suitable for biomedical applications such as wound healing. In particular, the electrospun silk fibroin/PEO mats with a silk:PEO blend ratio of 2:1 to 4:1, treated with controlled evaporation, constraint-drying techniques, and/or alcohol treatment, and/or PEO extraction, demonstrate suitable physical and biofunctional properties, such as fiber structure, topography, absorption, water vapor transmission rates, oxygen permeation, and biodegradability, relevant to biomaterial systems with utility for wound dressings.