The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 13, 2014

Filed:

Apr. 23, 2010
Applicants:

Eric M. Ostertag, Lexington, KY (US);

John Stuart Crawford, Lexington, KY (US);

Inventors:

Eric M. Ostertag, Lexington, KY (US);

John Stuart Crawford, Lexington, KY (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/00 (2006.01); A01K 67/027 (2006.01); C12N 15/85 (2006.01);
U.S. Cl.
CPC ...
A01K 67/0278 (2013.01); A01K 2217/075 (2013.01); A01K 2217/203 (2013.01); C12N 15/85 (2013.01); C12N 2015/8527 (2013.01); C12N 2015/8536 (2013.01); C12N 2015/8572 (2013.01);
Abstract

This invention relates to the engineering of animal cells, preferably mammalian, more preferably rat, that are deficient due to the disruption of tumor suppressor gene(s) or gene product(s). In another aspect, the invention relates to genetically modified rats, as well as the descendants and ancestors of such animals, which are animal models of human cancer and methods of their use.


Find Patent Forward Citations

Ostertag, Eric. (2014). Genetically engineered or transgenic rats exhibiting a cancer phenotype due to a disruption of germline tumor suppressor genes (U.S. Patent No. 8722964). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/8722964

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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