The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 8722919 B1

PDF
Full Text
Expired
Date of Patent:
May. 13, 2014

Filed:

Jul. 28, 2006
Applicants:

Keiji Maruoka, Kyoto, JP;

Toru Inoue, Kobe, JP;

Jun Matsumoto, Kobe, JP;

Inventors:

Keiji Maruoka, Kyoto, JP;

Toru Inoue, Kobe, JP;

Jun Matsumoto, Kobe, JP;

Assignee:

Nagase & Co., Ltd., Osaka-shi, JP;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07C 251/24 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention provides a method for producing asymmetrical mono-substituted alkylated compounds of α-amino acids that are represented by a specific formula, using an aldimine-type Schiff base. In the method of the present invention, the process of alkylating an aldimine-type Schiff base in a medium in the presence of an optically-active quaternary ammonium salt phase-transfer catalyst and an inorganic base is initiated, and subsequently the reaction is quenched at a time earlier than a time for completion of the stoichiometric reaction of the alkylation reaction, so that a mono-substituted alkylated product with high optical purity can be obtained.


Find Patent Forward Citations

Maruoka, Keiji. (2014). Process for production of mono-substituted alkylated compound using aldimine or derivative thereof (U.S. Patent No. 8722919). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/8722919

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