The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 13, 2014

Filed:

Feb. 05, 2010
Applicants:

Gerard Griffioen, Linden, BE;

Veronica Rojas DE LA Parra, Haasrode, BE;

Annick Lauwers, Herent, BE;

Inventors:

Gerard Griffioen, Linden, BE;

Veronica Rojas De La Parra, Haasrode, BE;

Annick Lauwers, Herent, BE;

Assignee:

NV reMYND, Heverlee, BE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/496 (2006.01); C07D 277/42 (2006.01); C07D 417/12 (2006.01); A61K 31/454 (2006.01);
U.S. Cl.
CPC ...
Abstract

This invention provides thiazolylpiperazine derivatives, and N-sulfonyl heterocyclic derivatives including phenyl- and benzyl-thiazolylpiperidine derivatives, and pharmaceutically acceptable salts thereof, which are useful active ingredients for administration in a method for the treatment of an α-synucleopathy such as Parkinson's disease, diffuse Lewy body disease, traumatic brain injury, amyotrophic lateral sclerosis, Niemann-Pick disease, Hallervorden-Spatz syndrome, Down syndrome, neuroaxonal dystrophy, multiple system atrophy and Alzheimer's disease. This invention also provides methods for making such derivatives, and pharmaceutical compositions including such derivatives together with pharmaceutically acceptable excipients.


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