The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 13, 2014
Filed:
Jun. 07, 2012
Applicants:
Jennifer R. Grandis, Pittsburgh, PA (US);
Daniel Johnson, Glenshaw, PA (US);
Danith Ly, Pittsburgh, PA (US);
Inventors:
Jennifer R. Grandis, Pittsburgh, PA (US);
Daniel Johnson, Glenshaw, PA (US);
Danith Ly, Pittsburgh, PA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 21/02 (2006.01); C07H 21/04 (2006.01); C12N 15/115 (2010.01); C12Q 1/68 (2006.01);
U.S. Cl.
CPC ...
C12N 15/115 (2013.01);
Abstract
The present invention is based, at least in part, on novel, unimolecular STAT3 oligonucleotide decoys exhibiting increased in vivo stability as compared to previously known decoys which are effective in inhibiting STAT3 when administered systemically. The invention is also based on pharmaceutical compositions comprising these unimolecular decoys, and methods for using these decoys in the treatment of cancer.