The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 13, 2014
Filed:
Jan. 14, 2009
Yang YE, Shanghai, CN;
Minjia Tan, Shanghai, CN;
Changqiang KE, Shanghai, CN;
Tong Chen, Shanghai, CN;
Xiqiang LI, Shanghai, CN;
Edward Kraegen, Sydney, AU;
Jiming YE, Sydney, AU;
David James, Sydney, AU;
Gregory Cooney, Sydney, AU;
Yang Ye, Shanghai, CN;
Minjia Tan, Shanghai, CN;
Changqiang Ke, Shanghai, CN;
Tong Chen, Shanghai, CN;
Xiqiang Li, Shanghai, CN;
Edward Kraegen, Sydney, AU;
Jiming Ye, Sydney, AU;
David James, Sydney, AU;
Gregory Cooney, Sydney, AU;
Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, CN;
The Garvan Institute of Medical Research, Australia, Sydney, AU;
Abstract
The present invention disclosed a medical use of cucurbitane triterpenoids represented by the following formula and isolated fromL. of Cucurbitaceae family in the preparation of medications for prevention and treatment of diabetes and obesity. The above cucurbitane triterpenoids may be acted as a glucose uptake stimulator, an agonist for the translocation of glucose transporter 4 (GLUT4) to the cell membrane, and an activator of adenosine monophosphate-activated protein kinase (AMPK). They may have potential for the prevention and treatment of diabetes and obesity.