The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 13, 2014
Filed:
Apr. 27, 2012
Applicants:
Steven Jacobs, Radnor, PA (US);
Karyn O'neil, Radnor, PA (US);
Michael Baumann, Zurich, CH;
Gaby Sennhauser, Pfaffikon, CH;
Inventors:
Steven Jacobs, Radnor, PA (US);
Karyn O'Neil, Radnor, PA (US);
Michael Baumann, Zurich, CH;
Gaby Sennhauser, Pfaffikon, CH;
Assignee:
Janssen Biotech, Inc., Horsham, PA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 15/24 (2006.01); C07K 14/00 (2006.01); A61P 11/00 (2006.01); A61P 11/06 (2006.01); A61P 9/00 (2006.01); A61P 35/00 (2006.01); C12P 21/02 (2006.01); C12N 15/11 (2006.01); C12N 15/63 (2006.01); C12N 1/21 (2006.01); C12N 1/19 (2006.01); C12N 7/01 (2006.01); C12N 5/10 (2006.01); A61K 38/16 (2006.01); A61P 17/00 (2006.01);
U.S. Cl.
CPC ...
Abstract
IL4/IL13-binding proteins comprise binding domains, which inhibit IL4/IL13 binding to IL4Ralpaha and common gamma chain complexes (Type 1) and inhibit IL4 binding to IL4Ralpha and IL13Ralpha1 complexes (Type 2), and IL13 binding to IL13Ralpha1 and/or IL13Ralpha2, are useful in the treatment of cancer, inflammatory, and other pathological conditions, such as allergic or fibrotic conditions, especially pulmonary conditions.