The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 13, 2014
Filed:
Apr. 18, 2006
Hervé Groux, Le Rouret, FR;
Françoise Cottrez, Le Rouret, FR;
Hervé Bastian, Auribeau sur Siagne, FR;
Valérie Brun, Biot, FR;
Hervé Groux, Le Rouret, FR;
Françoise Cottrez, Le Rouret, FR;
Hervé Bastian, Auribeau sur Siagne, FR;
Valérie Brun, Biot, FR;
TxCell, Sophia Antipolis, FR;
Institut National de la Sante et de la Recherche Medicale (INSERM), Paris, FR;
Abstract
A method for the in vitro production of a cell population P' from a cell population P, the production requiring the presence of at least one factor which is expressed by feeder cells, wherein a) feeder cells proliferate at a temperature T, b) proliferated feeder cells are contacted with the cell population P, c) the cell mixture obtained at step (b) is cultivated at a temperature Twhich is chosen such that the cell population P proliferates and the feeder cells do not proliferate, the at least one factor being expressed by the feeder cells, and d) the cell population P′ so produced is recovered. Advantageously, the production consists in an expansion, the feeder cells are insect feeder cells and the cell population P to be expanded is a T lymphocyte population, preferably a Trl lymphocyte population.