The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 13, 2014

Filed:

Dec. 31, 2008
Applicants:

Ronaldus Adrianus Maria Fouchier, Rotterdam, NL;

Bernadetta Gerarda Van Den Hoogen, Rotterdam, NL;

Albertus Dominicus Marcellinus Erasmus Osterhaus, Bunnik, NL;

Aurelia Haller, Redwood City, CA (US);

Roderick Tang, San Carlos, CA (US);

Inventors:

Ronaldus Adrianus Maria Fouchier, Rotterdam, NL;

Bernadetta Gerarda Van Den Hoogen, Rotterdam, NL;

Albertus Dominicus Marcellinus Erasmus Osterhaus, Bunnik, NL;

Aurelia Haller, Redwood City, CA (US);

Roderick Tang, San Carlos, CA (US);

Assignees:

ViroNovative B.V., Rotterdam, NL;

MedImmune Vaccines, Inc., Mountain View, CA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 16/00 (2006.01); C07K 16/10 (2006.01); G01N 33/53 (2006.01);
U.S. Cl.
CPC ...
Abstract

Provided is an isolated mammalian negative strand RNA virus,(MPV). Described are isolated mammalian negative strand RNA viruses identifiable as phylogenetically corresponding or relating to the genusand components thereof. Also described is mammalian MPV, subgroups and variants thereof, and genomic nucleotide sequences of different isolates of mammalian metapneumoviruses, in particular human metapneumoviruses. The use of the sequence information of different isolates of mammalian metapneumoviruses for diagnostic and therapeutic methods is provided. Nucleotide sequences encoding the genome of aor a portion thereof, including both mammalian and avianare described. Also provided are chimeric or recombinant viruses encoded by said nucleotide sequences and chimeric and recombinant mammalian MPV that comprise one or more non-native or heterologous sequences.


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