The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 13, 2014
Filed:
Mar. 07, 2008
Elisabeth Arkenau-marić, Köln, DE;
Johannes Bartholomaeus, Aachen, DE;
Iris Ziegler, Neusäβ, DE;
Marcel Haupts, Stolberg, DE;
Elisabeth Arkenau-Marić, Köln, DE;
Johannes Bartholomaeus, Aachen, DE;
Iris Ziegler, Neusäβ, DE;
Marcel Haupts, Stolberg, DE;
Gruenenthal GmbH, Aachen, DE;
Abstract
A multiparticulate dosage form formulated to make misuse more difficult containing least one active substance with potential for misuse (A), at least one synthetic or natural polymer (C), optionally at least one natural, semi-synthetic or synthetic wax (D), at least one disintegrant (E) and optionally one or more additional physiologically compatible excipients (B), wherein the individual particles of the dosage form display a breaking strength of at least 500 N and a release of active substance of at least 75% after 45 minutes measured according to Ph.Eur. in the paddle mixer with sinker in 600 ml of aqueous buffer solution with a pH value of 1.2 at 37° C. and 75 rpm.