The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 13, 2014
Filed:
Feb. 17, 2012
Juan Carlos Almagro, Brookline, MA (US);
Glenn Mark Anderson, Radnor, PA (US);
Ellen Chi, San Diego, CA (US);
Christian Martinez, San Diego, CA (US);
Gopalan Raghunathan, San Diego, CA (US);
Ronald Swanson, San Diego, CA (US);
Alexey Teplyakov, Radnor, PA (US);
Kam-fai Tse, Radnor, PA (US);
Sheng-jiun Wu, Radnor, PA (US);
Hong Mimi Zhou, San Diego, CA (US);
Juan Carlos Almagro, Brookline, MA (US);
Glenn Mark Anderson, Radnor, PA (US);
Ellen Chi, San Diego, CA (US);
Christian Martinez, San Diego, CA (US);
Gopalan Raghunathan, San Diego, CA (US);
Ronald Swanson, San Diego, CA (US);
Alexey Teplyakov, Radnor, PA (US);
Kam-Fai Tse, Radnor, PA (US);
Sheng-Jiun Wu, Radnor, PA (US);
Hong Mimi Zhou, San Diego, CA (US);
Janssen Biotech, Inc., Horsham, PA (US);
Abstract
The invention relates to a humanized form of an antibody capable of preventing tissue factor (coagulation factor F3) signaling but which does not interfere with Factor VII binding or FX binding to tissue factor and does not prolong coagulation time. The antibody of the invention is useful in treating conditions, such as tumor progression, in which the associated cells express tissue factor and tissue factor signaling occurs.