The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 13, 2014

Filed:

Mar. 29, 2011
Applicants:

Michael A. Matthews, Columbia, SC (US);

Jian Zhang, Sunnyvale, CA (US);

Aidaris Jimenez, Hamilton, OH (US);

Inventors:

Michael A. Matthews, Columbia, SC (US);

Jian Zhang, Sunnyvale, CA (US);

Aidaris Jimenez, Hamilton, OH (US);

Assignee:

University of South Carolina, Columbia, SC (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61L 2/00 (2006.01); B08B 7/00 (2006.01); B08B 9/093 (2006.01); A01N 1/02 (2006.01); A61K 8/22 (2006.01); A61L 2/20 (2006.01); A61K 31/337 (2006.01); A61K 31/70 (2006.01); A61K 31/7088 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
A01N 1/0215 (2013.01); A61K 8/22 (2013.01); A61L 2/00 (2013.01); A61L 2/208 (2013.01); A61K 2300/00 (2013.01); A61K 31/337 (2013.01); A61K 31/70 (2013.01); A61K 31/7088 (2013.01); A61K 45/06 (2013.01);
Abstract

Methods for sterilizing a biocompatible hydrogel polymer are provided via treating the biocompatible hydrogel polymer with a supercritical COtreatment composition at a treatment pressure of about 4 MPa to about 30 MPa and a treatment temperature of about 5° C. to about 75° C. The supercritical COtreatment composition can be substantially pure COor may further include hydrogen peroxide (e.g., in an amount of about 10 ppm to about 1,000 ppm). In certain embodiments, the biocompatible hydrogel polymer can be treated with the supercritical COtreatment composition for about 30 minutes to about 5 hours. According to these methods, treating the biocompatible hydrogel polymer can kill about 90% or more of anyandpresent in the biocompatible hydrogel polymer.


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