The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 06, 2014

Filed:

Feb. 19, 2009
Applicants:

Alan B. Cooper, Kenilworth, NJ (US);

Yang Nan, Cambridge, MA (US);

Yongqi Deng, Cambridge, MA (US);

Gerald W. Shipps, Jr., Cambridge, MA (US);

Neng-yang Shih, Cambridge, MA (US);

Hugh Y. Zhu, Kenilworth, NJ (US);

Jagdish A. Desai, Kenilworth, NJ (US);

James J-s Wang, Kenilworth, NJ (US);

Sunil Paliwal, Kenilworth, NJ (US);

Hon-chung Tsui, Kenilworth, NJ (US);

Sobhana Babu Boga, Kenilworth, NJ (US);

Abdul-basit Alhassan, Kenilworth, NJ (US);

Xiaolei Gao, Kenilworth, NJ (US);

Liang Zhu, Cambridge, MA (US);

Ahmed Samatar, West Windsor, NJ (US);

Inventors:

Alan B. Cooper, Kenilworth, NJ (US);

Yang Nan, Cambridge, MA (US);

Yongqi Deng, Cambridge, MA (US);

Gerald W. Shipps, Jr., Cambridge, MA (US);

Neng-Yang Shih, Cambridge, MA (US);

Hugh Y. Zhu, Kenilworth, NJ (US);

Jagdish A. Desai, Kenilworth, NJ (US);

James J-S Wang, Kenilworth, NJ (US);

Sunil Paliwal, Kenilworth, NJ (US);

Hon-Chung Tsui, Kenilworth, NJ (US);

Sobhana Babu Boga, Kenilworth, NJ (US);

Abdul-Basit Alhassan, Kenilworth, NJ (US);

Xiaolei Gao, Kenilworth, NJ (US);

Liang Zhu, Cambridge, MA (US);

Ahmed Samatar, West Windsor, NJ (US);

Assignee:

Merck Sharp & Dohme Corp., Rahway, NJ (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 401/04 (2006.01); A61K 31/444 (2006.01);
U.S. Cl.
CPC ...
Abstract

Disclosed are the ERK inhibitors of formula 1.0: and the pharmaceutically acceptable salts, and solvates thereof. Q is a tetrahydropyridinyl ring. All other substitutents are as defined herein. Also disclosed are methods of treating cancer using the compounds of formula 1.0.


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