The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 06, 2014
Filed:
May. 26, 2010
Robert George Boyle, Cambridge, GB;
David Winter Walker, Cambridge, GB;
Robert George Boyle, Cambridge, GB;
David Winter Walker, Cambridge, GB;
Sentinel Oncology Limited, , GB;
Abstract
The invention provides compounds of the formula (1): or salts or tautomers thereof; wherein Xis N or N(O); Xis N or CH; Q is a Calkylene group; Ris selected from hydrogen, Chydrocarbyl and hydroxy-Chydrocarbyl; R, Rand Rare the same or different and each is selected from hydrogen, fluorine, chlorine and methyl; Aris an optionally substituted monocyclic 5 or 6-membered aryl or heteroaryl ring containing 0, 1 or 2 heteroatom ring members selected from O, N and S, or a naphthyl ring and Aris an optionally substituted monocyclic 5 or 6-membered heteroaryl ring containing 1, 2 or 3 heteroatom ring members selected from O, N and S. The compounds of formula (1) are inhibitors of p70S6 kinase and are useful in the treatment of proliferative diseases.