The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 06, 2014
Filed:
May. 07, 2009
Pierre Druilhe, Paris, FR;
Giampietro Corradin, Lausanne, CH;
Ali Jafarshad, Paris, FR;
Christian Roussilhon, Paris, FR;
Pierre Druilhe, Paris, FR;
Giampietro Corradin, Lausanne, CH;
Ali Jafarshad, Paris, FR;
Christian Roussilhon, Paris, FR;
Institut Pasteur, Paris, FR;
Univiersite de Lausanne, Lausanne, CH;
Abstract
The present application relates to a sub-region of aprotein, with improved vaccine potential, and to medical uses thereof, notably for treatment or diagnosis of malaria. The present invention notably provides unstructured or unfolded polypeptides deriving from the PFF0165c protein of3D7. The polypeptides of the invention have a high antigenicity, a high immunogenicity, have a high parasite-killing activity in the ADCI assay, and are strongly associated with clinical protection against malaria, and. The present invention thereby provides a vaccine for the palliative and/or curative treatment of malaria, which is specifically intended for infants, toddlers, children under the age of 5, pregnant women.