The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 06, 2014

Filed:

Apr. 28, 2011
Applicants:

Joaquin Pastor-fernández, Toledo, ES;

José Manuel Bartolomé-nebreda, Toledo, ES;

Gregor James Macdonald, Zoersel, BE;

Susana Conde-ceide, Toledo, ES;

Óscar Delgado-gonzález, Valencia, ES;

Greta Constantia Peter Vanhoof, Zoersel, BE;

Michiel Luc Maria Van Gool, Madrid, ES;

María Luz Martín-martín, Salamanca, ES;

Sergio-alvar Alonso-de Diego, Madrid, ES;

Kelly Ann Swinney, Pulle, BE;

Carina Leys, Stabroek, BE;

Johan Erwin Edmond Weerts, Beerse, BE;

Stijn Wuyts, Oostham, BE;

Inventors:
Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/5025 (2006.01); A61K 31/5377 (2006.01); C07D 413/14 (2006.01); C07D 403/14 (2006.01); C07D 487/04 (2006.01);
U.S. Cl.
CPC ...
C07D 487/04 (2013.01);
Abstract

The present invention relates to novel imidazo[1,2-]pyridazine derivatives which are inhibitors of the phosphodiesterase 10 enzyme (PDE10) and which are useful for the treatment or prevention of neurological, psychiatric and metabolic disorders in which the PDE10 enzyme is involved. The invention is also directed to pharmaceutical compositions comprising such compounds, to processes to prepare such compounds and compositions, to the use of such compounds or pharmaceutical compositions for the prevention or treatment of neurological, psychiatric and metabolic disorders and diseases.


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