The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 06, 2014

Filed:

May. 12, 2009
Applicants:

Kenichi Masuda, Kanagawa, JP;

Yasuyuki Ishii, Kanagawa, JP;

Nobutaka Yasuda, Kanagawa, JP;

Inventors:

Kenichi Masuda, Kanagawa, JP;

Yasuyuki Ishii, Kanagawa, JP;

Nobutaka Yasuda, Kanagawa, JP;

Assignees:

RIKEN, Wako, JP;

Animal Allergy Clinical Laboratories, Sagamihara, JP;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 16/06 (2006.01); C07K 16/42 (2006.01); G01N 33/53 (2006.01); G01N 33/536 (2006.01); G01N 33/537 (2006.01); G01N 33/543 (2006.01); G01N 33/563 (2006.01); G01N 33/96 (2006.01); G01N 33/68 (2006.01); C12N 5/20 (2006.01); C12N 5/16 (2006.01);
U.S. Cl.
CPC ...
G01N 33/6854 (2013.01); G01N 33/96 (2013.01); G01N 33/536 (2013.01); G01N 33/537 (2013.01); G01N 33/543 (2013.01); G01N 2333/435 (2013.01); G01N 2469/20 (2013.01); G01N 2496/05 (2013.01); G01N 2800/24 (2013.01); C07K 16/06 (2013.01); C07K 16/42 (2013.01); C07K 16/4291 (2013.01); C12N 5/163 (2013.01); Y10S 435/975 (2013.01);
Abstract

Disclosed is a convenient and effective means for quantifying an antigen-specific canine or human IgE. Specifically disclosed is a method for quantifying an antigen-specific canine IgE, which comprises the following steps (A) to (D): (A) contacting a biological sample collected from a subject with an antigen to conjugate IgE contained in the sample with the antigen; (B) measuring the quantity of IgE in a standard sample collected from an experimental animal which is different from the subject and has been sensitized with the same antigen as that used in step (A) by using a substance capable of recognizing both IgE from the subject and IgE from the experimental animal, thereby producing a standard curve; (C) detecting a conjugate formed in step (A) by using the same substance capable of recognizing both IgE from the subject and IgE from the experimental animal as that used in step (B); and (D) determining the quantity of IgE in the biological sample collected from the subject by utilizing the quantity of the conjugate detected in step (C) and the standard curve produced in step (B). Also specifically disclosed is a method for quantifying an antigen-specific human IgE.


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