The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 06, 2014
Filed:
Mar. 31, 2010
Jung Tae Lee, Daejeon, KR;
Kyung Duk Moon, Daejeon, KR;
Ji Yong Yoon, Daejeon, KR;
Byung Je Sung, Daejeon, KR;
Dong Heon Lee, Daejeon, KR;
IL Sun Lee, Daejeon, KR;
Dong Eun Lee, Busan, KR;
Su Yeon Ryu, Daejeon, KR;
Young Woo Park, Daejeon, KR;
SO Young Choi, Daejeon, KR;
Ji Hyun Park, Gyeongsangnam-do, KR;
Myeoung Hee Jang, Daejeon, KR;
Jung Tae Lee, Daejeon, KR;
Kyung Duk Moon, Daejeon, KR;
Ji Yong Yoon, Daejeon, KR;
Byung Je Sung, Daejeon, KR;
Dong Heon Lee, Daejeon, KR;
Il Sun Lee, Daejeon, KR;
Dong Eun Lee, Busan, KR;
Su Yeon Ryu, Daejeon, KR;
Young Woo Park, Daejeon, KR;
So Young Choi, Daejeon, KR;
Ji Hyun Park, Gyeongsangnam-do, KR;
Myeoung Hee Jang, Daejeon, KR;
Hanwha Chemical Corporation, Seoul, KR;
Abstract
The present invention relates to a human monoclonal antibody that specifically binds to VCAM-1, and a therapeutic composition for the treatment of inflammatory disease or cancer comprising the same. The human monoclonal antibody according to the present invention shows a strong affinity to VCAM-1 expressed on human or mouse endothelial cell, effectively inhibits leukocyte adhesion to activated endothelial cells expressing VCAM-1, and shows a low immunogenicity, thereby being used for the treatment of cancer or inflammatory disease such as asthma, rhinitis, arthritis, multiple sclerosis, bowel disease, arteriosclerosis, myocardial infarction and transplant rejection.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile