The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 06, 2014

Filed:

May. 16, 2012
Applicants:

Jiong Wu, Los Gatos, CA (US);

Mahesh Junnarkar, Santa Clara, CA (US);

Giacomo Vacca, San Jose, CA (US);

Inventors:

Jiong Wu, Los Gatos, CA (US);

Mahesh Junnarkar, Santa Clara, CA (US);

Giacomo Vacca, San Jose, CA (US);

Assignee:

Abbott Laboratories, Abbott Park, IL (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N 21/64 (2006.01); G01N 15/06 (2006.01); G06K 9/00 (2006.01); G01N 15/02 (2006.01); G01N 21/49 (2006.01); G01N 21/85 (2006.01); G01J 3/30 (2006.01); G01N 21/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

Systems and methods for the detection, analysis, and collection of rare cellular events, wherein rare cellular events are defined by events comprising less than 5% of a total number of cells in a sample. The systems and methods generally include: (1) a flow cell dimensioned so as to permit a flow of a sample through the flow cell at a flow rate greater than 300,000 cells per second; (2) a laser positioned to emit a laser beam directed to the flow cell; (3) one or more deflector components disposed between the laser and the flow cell, wherein the deflector component is configured to affect a position of the laser beam relative to the sample flow; (4) one or more fluorescence emission detectors; and (5) one or more processor configured to detect rare cellular events based on fluorescence emission from cell-binding surface markers introduced into the sample prior to the sample being flowed through the flow cell.


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