The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 29, 2014

Filed:

Apr. 19, 2007
Applicants:

Cecil Pace-asciak, Toronto, CA;

Alexandra Santana Sorensen, Allschwil, CH;

Jean-philippe Meyer, Strasbourg, FR;

Peter Denim, Moscow, RU;

Inventors:

Cecil Pace-Asciak, Toronto, CA;

Alexandra SantAna Sorensen, Allschwil, CH;

Jean-Philippe Meyer, Strasbourg, FR;

Peter Denim, Moscow, RU;

Assignee:

Other;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07C 57/00 (2006.01); C07C 59/11 (2006.01); A61K 31/20 (2006.01); C07C 69/74 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to enantiomeric forms of hepoxilin analogs of Formula I-VIII, pharmaceutical compositions thereof, a method for the separation of said enantiomeric forms of hepoxilin analogs comprising applying said hepoxilin to a chiral phase HPLC column and eluting said hepoxilin with an alkane and alcohol solvent mixture. Said enantiomeric forms of hepoxilin analogs of Formula I-VIII were found to be useful in controlling the biological effects of PPAR mediated transcriptional control for the treatment of diseases such as cancer, thromboxane-mediated diseases and for modulating intracellular calcium concentration.


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