The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 29, 2014
Filed:
Oct. 18, 2010
Kazuhiro Irie, Kyoto, JP;
Kazuma Murakami, Kyoto, JP;
Yuichi Masuda, Kyoto, JP;
Takahiko Shimizu, Tokyo, JP;
Takuji Shirasawa, Tokyo, JP;
Tsutomu Seito, Fujioka, JP;
Kazuhiro Irie, Kyoto, JP;
Kazuma Murakami, Kyoto, JP;
Yuichi Masuda, Kyoto, JP;
Takahiko Shimizu, Tokyo, JP;
Takuji Shirasawa, Tokyo, JP;
Tsutomu Seito, Fujioka, JP;
Kyoto University, Kyoto, JP;
Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology, Tokyo, JP;
Immuno-Biological Laboratories Co., Ltd., Gunma, JP;
Abstract
Provided is a therapeutic method exclusively targeting an amyloid β protein (Aβ) having a specific turn structure of Aβ. Specifically provided is an antibody which specifically recognizes an amyloid β having a turn structure at amino acids positions 22 and 23. Also provided are a medicinal composition comprising, as the active ingredient, an antibody specifically recognizing a toxic conformer of amyloid β, an assay kit for a toxic conformer of amyloid β, a diagnostic for Alzheimer's disease, etc.