The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 29, 2014
Filed:
Nov. 28, 2011
Applicants:
Robert G. Ulrích, Frederick, MD (US);
Mark A. Olson, Gaithersburg, MD (US);
Sina Bavari, Dillsburg, PA (US);
Inventors:
Robert G. Ulrích, Frederick, MD (US);
Mark A. Olson, Gaithersburg, MD (US);
Sina Bavari, Dillsburg, PA (US);
Assignee:
The United States of America as represented by the Secretary of the Army, Washington, DC (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/31 (2006.01);
U.S. Cl.
CPC ...
Abstract
The present invention relates to genetically attenuated superantigen toxin vaccines altered such that superantigen attributes are absent, however the superantigen is effectively recognized and an appropriate immune response is produced. The attenuated superantigen toxins are shown to protect animals against challenge with wild type toxin. Methods of producing and using the altered superantigen toxins are described.