The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 29, 2014
Filed:
Dec. 23, 2010
Jian Zhang, Sunnyvale, CA (US);
Robert O. Cook, Hillsborough, NJ (US);
Thomas A. Armer, Cupertino, CA (US);
Sergey Alexandrovich Kosarev, Singapore, SG;
Dejian Xie, Shanghai, CN;
Jian Zhang, Sunnyvale, CA (US);
Robert O. Cook, Hillsborough, NJ (US);
Thomas A. Armer, Cupertino, CA (US);
Sergey Alexandrovich Kosarev, Singapore, SG;
Dejian Xie, Shanghai, CN;
Map Pharmaceuticals, Inc., Irvine, CA (US);
Abstract
Provided herein are substituted indolo[4,3-fg]quinolines of Formula (I) and (II) where R-Rand Rare as defined in the specification and pharmaceutical compositions thereof which are useful in treating, preventing, or ameliorating a variety of medical disorders such as, for example, migraine. In other embodiments, provided herein are methods of agonizing receptors such as, for example, the 5-HTand or 5-HTreceptor using the compounds and compositions disclosed herein. In still other embodiments, provided herein are methods of antagonizing or inhibiting activity at receptors such as, for example, the 5-HTreceptor using the compounds and compositions disclosed herein. In still other embodiments, provided herein are methods of regulating serotonin transport using the compounds and compositions disclosed herein.