The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 29, 2014
Filed:
Jan. 19, 2010
Alan Berezov, West Hollywood, CA (US);
Qiang Wang, North Hollywood, CA (US);
Ramachandran Murali, Los Angeles, CA (US);
Mark I. Greene, Penn Valley, PA (US);
Alan Berezov, West Hollywood, CA (US);
Qiang Wang, North Hollywood, CA (US);
Ramachandran Murali, Los Angeles, CA (US);
Mark I. Greene, Penn Valley, PA (US);
The Trustees Of The University Of Pennsylvania, Philadelphia, PA (US);
Abstract
Disclosed herein are methods of treating cancer by administering to a patient a small molecule inhibitor of Survivin. Also disclosed herein are methods of inhibiting Survivin dimerization in a patient by administering a compound of formula (I), (II), (III), or (IV). Methods of inducing cell cycle arrest in cancer cells, comprising G2/M stage arrest, in a patient by administering a compound of formula (I), (II), (III), or (IV) are also disclosed. Further disclosed herein are methods of inducing apoptosis in cancer cells in a patient by administering a compound of formula (I), (II), (III), or (IV).