The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 29, 2014

Filed:

Sep. 15, 2005
Applicants:

Tae-gon Baik, Foster City, CA (US);

Chris A. Buhr, Redwood City, CA (US);

Sunghoon MA, Foster City, CA (US);

John M. Nuss, Danville, CA (US);

Zerom Tesfai, Castro Valley, CA (US);

Longcheng Wang, Palo Alto, CA (US);

Bryan K. S. Yeung, Chromos, SG;

Inventors:

Tae-Gon Baik, Foster City, CA (US);

Chris A. Buhr, Redwood City, CA (US);

Sunghoon Ma, Foster City, CA (US);

John M. Nuss, Danville, CA (US);

Zerom Tesfai, Castro Valley, CA (US);

Longcheng Wang, Palo Alto, CA (US);

Bryan K. S. Yeung, Chromos, SG;

Assignee:

Exelixis, Inc., South San Francisco, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 403/00 (2006.01); A01N 43/00 (2006.01); A61K 31/33 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention provides compounds for modulating protein kinase enzymatic activity for modulating cellular activities such as proliferation, differentiation, programmed cell death, migration and chemoinvasion. Compounds of the invention inhibit, regulate and/or modulate kinases. Methods of using the compounds and pharmaceutical compositions thereof to treat kinase-dependent diseases and conditions are also an aspect of the invention.


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