The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 29, 2014
Filed:
Feb. 08, 2008
Richard S Larson, Albuquerque, NM (US);
Brian Hjelle, Placitas, NM (US);
Pam R Hall, Albuquerque, NM (US);
David C Brown, Albuquerque, NM (US);
Marco Bisoffi, Albuquerque, NM (US);
Susan M Brozik, Albuquerque, NM (US);
Darren W Branch, Albuquerque, NM (US);
Thayne L Edwards, Albuquerque, NM (US);
David Wheeler, Albuquerque, NM (US);
Richard S Larson, Albuquerque, NM (US);
Brian Hjelle, Placitas, NM (US);
Pam R Hall, Albuquerque, NM (US);
David C Brown, Albuquerque, NM (US);
Marco Bisoffi, Albuquerque, NM (US);
Susan M Brozik, Albuquerque, NM (US);
Darren W Branch, Albuquerque, NM (US);
Thayne L Edwards, Albuquerque, NM (US);
David Wheeler, Albuquerque, NM (US);
STC.UNM, Albuquerque, NM (US);
Sandia National Laboratories, Albuquerque, NM (US);
Abstract
A biosensor combining the sensitivity of surface acoustic waves (SAW) generated at a frequency of 325 MHz with the specificity provided by antibodies and other ligands for the detection of viral agents. In a preferred embodiment, a lithium tantalate based SAW transducer with silicon dioxide waveguide sensor platform featuring three test and one reference delay lines was used to adsorb antibodies directed against Coxsackie virus B4 or the negative-stranded category A bioagent Sin Nombre virus (SNV). Rapid detection of increasing concentrations of viral particles was linear over a range of order of magnitude for both viruses, and the sensor's selectivity for its target was not compromised by the presence of confounding Herpes Simplex virus type 1 The biosensor was able to delect SNV at doses lower than the load of virus typically found in a human patient suffering from hantavirus cardiopulmonary syndrome (HCPS).