The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 29, 2014
Filed:
Sep. 29, 2009
Koichi Takahashi, Machida, JP;
Kazuaki Maeda, Machida, JP;
Noriyuki Izutani, Machida, JP;
Shinichi Yanagi, Machida, JP;
Yukiko Nakashima, Machida, JP;
Koichi Takahashi, Machida, JP;
Kazuaki Maeda, Machida, JP;
Noriyuki Izutani, Machida, JP;
Shinichi Yanagi, Machida, JP;
Yukiko Nakashima, Machida, JP;
Denka Seiken Co., Ltd., Tokyo, JP;
Abstract
The present invention aims to provide a method which enables efficient removal of impurities such as the host proteins from an influenza virus culture liquid by a simple operation, allowing separation and purification of an influenza virus antigen. The method of the present invention for producing a purified influenza virus antigen comprises the step of treating a sample containing an influenza virus with a surfactant, the step of bringing the sample after the treatment into contact with hydroxyapatite in the presence of the surfactant, and the step of recovering a hydroxyapatite-non-adsorbed fraction.