The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 29, 2014
Filed:
Jan. 31, 2011
Applicant:
Vladas Algirdas Bumelis, Vilnius, LT;
Inventor:
Vladas Algirdas Bumelis, Vilnius, LT;
Assignee:
Digna Biotech, S.L., Pamplona (Navarra), ES;
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12P 21/04 (2006.01); C12N 1/20 (2006.01); C12N 1/21 (2006.01); C07K 14/56 (2006.01); A61K 38/21 (2006.01);
U.S. Cl.
CPC ...
Abstract
A process for producing an interferon alpha 5 (IFNa5) protein by expression in an IFNa5 producinghost cell, wherein incorporation of an extra methionine residue in the N-terminal end of the polypeptide chain is minimized as well as the generation of its oxidized species is disclosed. The IFNa5 protein can be purified by an efficient process to render a biologically active IFNa5.