The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 29, 2014
Filed:
Feb. 16, 2010
Applicants:
Alexander Scheffold, Cologne, DE;
Sascha Rutz, Berlin, DE;
Frederick Heinrich, Berlin, DE;
Inventors:
Assignee:
Deutsches Rheuma-Forschungszentrum Berlin, Berlin, DE;
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/53 (2006.01); G01N 33/68 (2006.01); C12P 21/02 (2006.01); C12N 5/07 (2010.01); A61K 38/16 (2006.01); C07K 14/54 (2006.01); C07K 14/475 (2006.01); C07K 14/705 (2006.01);
U.S. Cl.
CPC ...
Abstract
The invention relates to the use of notch regulators for modulating IL-22 production in T-cells, by influencing the activity or activation of the notch signal path. The invention further relates to the use of modulating the immune response, primarily in case of infection reactions. The invention in particular relates to the use for treating illnesses associated with infections. The invention further relates to the use for reducing IL-22 production in T-cells.