The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 29, 2014

Filed:

Jul. 18, 2008
Applicants:

Michel Vert, Castelnau-le-lez, FR;

Laurent Leclercq, Montpellier, FR;

Mahfoud Boustta, Pignan, FR;

Inventors:

Michel Vert, Castelnau-le-lez, FR;

Laurent Leclercq, Montpellier, FR;

Mahfoud Boustta, Pignan, FR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/14 (2006.01); A61K 47/48 (2006.01); A61K 9/20 (2006.01);
U.S. Cl.
CPC ...
A61K 47/482 (2013.01); A61K 47/48207 (2013.01); A61K 9/204 (2013.01); A61K 9/2045 (2013.01);
Abstract

A system for controlled release of an active principle, includes at least (a) a degradable polymer matrix which produces acid compounds and (b) at least one acid-sensitive complex of an active principle having at least one electrostatic charge and a complexing polyelectrolyte partner of opposite charge which complexes with the active principle. A method for preparation of such a system is described. The release of the active principle (7P) is prolonged over 18 days (ternary system PMLA/7P/PLAGA) in comparison to binary systems (7P/PLAGA) and (PMLA/7P).


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