The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 29, 2014

Filed:

Jan. 28, 2010
Applicants:

Keith Redhead, Milton Keynes, GB;

Joachim Frey, Bern, CH;

Edy M. Vilei, Bern, CH;

Andreas Walter Claudius Rohwer, Schwabenheim, DE;

Anders Johansson, Bern, CH;

Inventors:

Keith Redhead, Milton Keynes, GB;

Joachim Frey, Bern, CH;

Edy M. Vilei, Bern, CH;

Andreas Walter Claudius Rohwer, Schwabenheim, DE;

Anders Johansson, Bern, CH;

Assignees:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/08 (2006.01); G01N 33/566 (2006.01); C07K 14/33 (2006.01); C07K 16/12 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention pertains to the identification and initial characterization of CctA, a novel, secreted toxin ofthat represents the major cytotoxic activity of. This toxin confersits characteristic strong hemolytic activity towards erythrocytes of various species, since anti-CctA antibodies fully neutralize hemolysis byon standard blood-agar medium or in cell-free supernatants of liquid cultures.


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