The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 29, 2014
Filed:
Jul. 08, 2011
Raffaela Campana, Vienna, AT;
Rudolf Valenta, Theresienfeld, AT;
Susanne Vrtala, Vienna, AT;
Ines Swoboda, Vienna, AT;
Margarete Focke-tejkl, Vienna, AT;
Anna Gieras, Vienna, AT;
Susanne Spitzauer, Vienna, AT;
Peter Valent, Vienna, AT;
Katharina Blatt, Grossenzersdorf, AT;
Birgit Linhart, Weissenkirchen, AT;
Dietrich Kraft, Vienna, AT;
Raffaela Campana, Vienna, AT;
Rudolf Valenta, Theresienfeld, AT;
Susanne Vrtala, Vienna, AT;
Ines Swoboda, Vienna, AT;
Margarete Focke-Tejkl, Vienna, AT;
Anna Gieras, Vienna, AT;
Susanne Spitzauer, Vienna, AT;
Peter Valent, Vienna, AT;
Katharina Blatt, Grossenzersdorf, AT;
Birgit Linhart, Weissenkirchen, AT;
Dietrich Kraft, Vienna, AT;
Biomay AG, Vienna, AT;
Abstract
Hypoallergenic mosaic antigens assembled from naturally-occurring allergens are disclosed herein. Also disclosed are methods of making such hypoallergenic mosaic antigens, particularly those derived from plant allergens such as timothy grass pollen (Phl p 1 and Phl p 2) and birch pollen (Bet v 1). In a particularly preferred embodiment, the method of making the hypoallergenic mosaic antigen involves the steps of (a) cleaving a naturally-occurring allergen into at least two, preferably at least three non-overlapping peptide fragments and (b) recombining the peptide fragments such that the mosaic antigen includes all or substantially all of the amino acids of the original naturally-occurring allergen, though in a different order.