The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 29, 2014

Filed:

Sep. 30, 2010
Applicants:

James Allison, New York, NY (US);

Padmanee Sharma, Bellaire, TX (US);

Sergio A. Quezada, Berkhamsted, GB;

Tihui Fu, Houston, TX (US);

Inventors:

James Allison, New York, NY (US);

Padmanee Sharma, Bellaire, TX (US);

Sergio A. Quezada, Berkhamsted, GB;

Tihui Fu, Houston, TX (US);

Assignees:

Memorial Sloan-Kettering Cancer Center, New York, NY (US);

Board of Regents, Austin, TX (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01); A61K 38/16 (2006.01); C12N 5/22 (2006.01);
U.S. Cl.
CPC ...
Abstract

Agonists to ICOS in combination with a blocking agent to a T cell inhibitory receptor (e.g., CTLA-4, PD-I, etc.) are demonstrated herein to be useful for the treatment of tumors.


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