The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 29, 2014
Filed:
Oct. 30, 2006
Daniel Scherman, Paris, FR;
Michel Bessodes, Villejuif, FR;
Corinne Chaneac, Bagnolet, FR;
Didier Louis Gourier, Paris, FR;
Jean-pierre Jolivet, Vaugrigneuse, FR;
Quentin Le Masne DE Chermont, Paris, FR;
Serge Maitrejean, Paris, FR;
Fabienne Sylvie Pelle, Colombes, FR;
Daniel Scherman, Paris, FR;
Michel Bessodes, Villejuif, FR;
Corinne Chaneac, Bagnolet, FR;
Didier Louis Gourier, Paris, FR;
Jean-Pierre Jolivet, Vaugrigneuse, FR;
Quentin Le Masne De Chermont, Paris, FR;
Serge Maitrejean, Paris, FR;
Fabienne Sylvie Pelle, Colombes, FR;
Abstract
The invention relates to using persistent luminescence nanoparticles, functionalised if necessary, in the form of an diagnosis agent for an in vivo optical imaging. Said nanoparticles are preferably consist of a compound selected from a group comprising (1) silicates, aluminates, aluminosilicates, germanates, titanates, oxysulphides, phosphates and vanadates, wherein said compounds contain at least one type of metal oxide, (2) the sulphides comprise at least one metal ion selected from zinc, strontium and calcium, and (3) metal oxides, wherein said compounds is doped with at least one rare earth ion, and possibly with at least one transition metal ion. In a preferred embodiment, the diagnosis agent is used for an organism vascularization imaging. A method and kit for detecting or quantifying in vitro a substance of biological or chemical interest in a sample by using said pre-functionalised nanoparticles are also disclosed.