The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 22, 2014

Filed:

Dec. 30, 2010
Applicants:

William J. Gordon-kamm, Urbandale, IA (US);

Keith S. Lowe, Johnston, IA (US);

David J. Peterson, Polk City, IA (US);

Christopher J. Scelonge, Ankeny, IA (US);

Grace M. St. Clair, Des Moines, IA (US);

Bing-bing Wang, Johnston, IA (US);

Inventors:

William J. Gordon-Kamm, Urbandale, IA (US);

Keith S. Lowe, Johnston, IA (US);

David J. Peterson, Polk City, IA (US);

Christopher J. Scelonge, Ankeny, IA (US);

Grace M. St. Clair, Des Moines, IA (US);

Bing-Bing Wang, Johnston, IA (US);

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 15/82 (2006.01); C12N 15/87 (2006.01); C12N 5/04 (2006.01); C12N 5/14 (2006.01); C07H 21/02 (2006.01);
U.S. Cl.
CPC ...
Abstract

A variety of methods and compostions are provided, including methods and compositions for targeted modification of a specific target site in a cell or organism, methods for integrating polynucleotides of interest, methods to assess promoter activity, directly select transformed organisms, minimize or eliminate expression resulting from random integration into the genome of an organism, such as a plant, remove polynucleotides of interest, combine multiple transfer cassettes, invert or excise a polynucleotide, silence a gene, and identify and/or characterize transcriptional regulating regions. The methods involve the introduction of a cell proliferation factor and a double-strand break-inducing enzyme into an organism.


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