The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 22, 2014
Filed:
May. 25, 2009
Nina Challand, Mannheim, DE;
Ansgar Gereon Altenhoff, Heidelberg, DE;
Joachim Schmidt-leithoff, Mannheim, DE;
Kathrin Wissel-stoll, Ludwigshafen, DE;
Michael Rack, Eppelheim, DE;
Joachim Rheinheimer, Ludwigshafen, DE;
Nina Challand, Mannheim, DE;
Ansgar Gereon Altenhoff, Heidelberg, DE;
Joachim Schmidt-Leithoff, Mannheim, DE;
Kathrin Wissel-Stoll, Ludwigshafen, DE;
Michael Rack, Eppelheim, DE;
Joachim Rheinheimer, Ludwigshafen, DE;
BASF SE, Ludwigshafen, DE;
Abstract
Process for the preparation of aromatic and heteroaromatic carboxylic acids, carboxylic acid esters and carboxamides by the reaction of aromatic or heteroaromatic halides R—X, in which n=integer from 1 to 6, R=substituted or unsubstituted and aromatic or heteroaromatic radical and X=chlorine, bromine or iodine atom, with carbon monoxide and water, ammonia, alcohols or amines in the presence of bases and zero-valent or divalent palladium compounds and bidentate diphosphanes or complexes of zero-valent or divalent palladium with bidentate diphosphanes, in which use is made of bidentate diphosphanes(R—)(R—)P—Y—P(—R)(—R)in which Rto R=unsubstituted aryl radicals or aryl radicals substituted with at least one radical exhibiting a positive resonance effect or a positive inductive effect, or unsubstituted or substituted cycloalkyl radicals, and Y=hydrocarbon group with a total of 2 to 20 carbon atoms, in which at least one of the carbon atoms carries only one or no hydrogen atom as substituent; except for the reaction of 4-bromo-3-difluoromethyl-1-methylpyrazole with 2-(3,4,5-trifluorophenyl)aniline and carbon monoxide to give N-[2-(3,4,5-trifluorophenyl)phenyl]-3-difluoromethyl-1-methylpyrazole-4-carboxamide.