The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 22, 2014
Filed:
Mar. 08, 2011
Young Lag Cho, Daejeon, KR;
Sung Yoon Baek, Daejeon, KR;
Sang Eun Chae, Daejeon, KR;
Hong Bum Lee, Daejeon, KR;
Tae Kyo Park, Daejeon, KR;
Sung Ho Woo, Daejeon, KR;
Yong Zu Kim, Daejeon, KR;
Young Lag Cho, Daejeon, KR;
Sung Yoon Baek, Daejeon, KR;
Sang Eun Chae, Daejeon, KR;
Hong Bum Lee, Daejeon, KR;
Tae Kyo Park, Daejeon, KR;
Sung Ho Woo, Daejeon, KR;
Yong Zu Kim, Daejeon, KR;
Legochem Biosciences, Inc., Daejeon, KR;
Abstract
Provided are a method for preparing (R)-3-(3-fluoro-4-(1-methyl-5, 6-dihydro-1,2,4-triazin-4(1H)-yl)phenyl)-5-(substituted methyl) oxazolidin-2-one derivatives, which are oxazolidinone antibiotic compounds having a cyclic amidrazone group, represented by Chemical Formula 1, and intermediates thereof, and uses 3,4-difluoro-4-nitrobenzen as a starting material. According to the preparation method of the present invention, (R)-3-(3-fluoro-4-(1-methyl-5, 6-dihydro-1,2,4-triazin-4(1H)-yl)phenyl)-5-(substituted methyl) oxazolidin-2-one derivatives, which are useful as oxazolidinone antibiotics, can be prepared in high purity and high yield in a simpler manner than conventional methods.