The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 8703936 B1

PDF
Full Text
Expired
Date of Patent:
Apr. 22, 2014

Filed:

Aug. 08, 2013
Applicant:

The Regents of the University of California, Oakland, CA (US);

Inventors:

John C. Jewett, Berkeley, CA (US);

Carolyn R. Bertozzi, Berkeley, CA (US);

Ellen May Sletten, Berkeley, CA (US);

Chelsea G. Gordon, Berkeley, CA (US);

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 225/04 (2006.01);
U.S. Cl.
CPC ...
Abstract

Provided are modified cycloalkyne compounds; and methods of use of such compounds in modifying biomolecules. Embodiments include a cycloaddition reaction that can be carried out under physiological conditions. The cycloaddition reaction involves reacting a modified cycloalkyne with an azide moiety on a target biomolecule, generating a covalently modified biomolecule. The selectivity of the reaction and its compatibility with aqueous environments provide for its application in vivo and in vitro.


Find Patent Forward Citations

Jewett, John. (2014). Compositions and methods for modification of biomolecules (U.S. Patent No. 8703936). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/8703936

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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