The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 22, 2014
Filed:
Feb. 27, 2012
Karlheinz Baumann, Efringen-Kirchen, DE;
Luke Green, Basel, CH;
Anja Limberg, Basel, CH;
Thomas Luebbers, Loerrach, DE;
Andrew Thomas, Binningen, CH;
Karlheinz Baumann, Efringen-Kirchen, DE;
Luke Green, Basel, CH;
Anja Limberg, Basel, CH;
Thomas Luebbers, Loerrach, DE;
Andrew Thomas, Binningen, CH;
Hoffmann-La Roche Inc., Nutley, NJ (US);
Abstract
The present invention relates to compounds of formula I hetaryl I, hetaryl II, R, R, R, Y,m, and o or to pharmaceutically active acid addition salts thereof. The present compounds of formula I are modulators for amyloid beta and thus, they may be useful for the treatment or prevention of a disease associated with the deposition of β-amyloid in the brain, in particular Alzheimer's disease, and other diseases such as cerebral amyloid angiopathy, hereditary cerebral hemorrhage with amyloidosis, Dutch-type (HCHWA-D), multi-infarct dementia, dementia pugilistica and Down syndrome.