The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 22, 2014
Filed:
Jun. 01, 2009
Merrill Jackson, Tucson, AZ (US);
Michael Herman, Tucson, AZ (US);
Grace Hoben, Marana, AZ (US);
Noemi Sebastiao, Tucson, AZ (US);
Scott Cockayne, Tucson, AZ (US);
Heather Ferrea, Tucson, AZ (US);
Merrill Jackson, Tucson, AZ (US);
Michael Herman, Tucson, AZ (US);
Grace Hoben, Marana, AZ (US);
Noemi Sebastiao, Tucson, AZ (US);
Scott Cockayne, Tucson, AZ (US);
Heather Ferrea, Tucson, AZ (US);
Ventana Medical Systems, Inc., Tucson, AZ (US);
Abstract
Histochemical process compositions comprising at least one nanoparticle in an amount effective to reduce or substantially eliminate the average number of spots per slide that result from a sample staining protocol are disclosed. Various nanoparticles, or combinations thereof, including metals, metal alloys, metal oxides, ceramics, functionalized metals or metalloids, and other miscellaneous nanoparticles, such as carbon nanoparticles and diamond nanoparticles, can be used. The nanoparticle concentration typically is from about 2 parts per million to about 20 parts per million. One embodiment of a disclosed method concerns applying a histochemical process composition to a sample, followed by performing a staining protocol on the sample. Particular embodiments concern dispensing a nanosolution onto a sample using an automated system, heating the sample, and performing a sample staining process.