The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 22, 2014
Filed:
Jun. 23, 2009
Daniel H. Maes, Huntington, NY (US);
Nadine A. Pernodet, Huntington, NY (US);
Thomas Mammone, Farmingdale, NY (US);
Edward Pelle, Valley Stream, NY (US);
Donald F. Collins, Plainview, NY (US);
Lenny Slutsky, Hauppauge, NY (US);
Kerri Goldgraben, Commack, NY (US);
Daniel H. Maes, Huntington, NY (US);
Nadine A. Pernodet, Huntington, NY (US);
Thomas Mammone, Farmingdale, NY (US);
Edward Pelle, Valley Stream, NY (US);
Donald F. Collins, Plainview, NY (US);
Lenny Slutsky, Hauppauge, NY (US);
Kerri Goldgraben, Commack, NY (US);
ELC Management, LLC, New York, NY (US);
Abstract
Compositions and methods for enhancing repair of damaged DNA in skin cells. Topical compositions comprising at least one agent that upregulates circadian gene expression in skin cells and at least one non-circadian agent that delays mitosis in skin cells. Preferably, such compositions comprise one or more keratinocyte clock and per1 gene activators, along with SIRT1 or one or more sirt1 activators. More preferably, the sirt1 activator is a synergistic combination of specific peptidic sirt1 activators and resveratrol. Preferably, such compositions are easy to use, efficacious, cosmetically acceptable, chemically, thermodynamically and light stable, safe for topical use, have little or no side effects, and commercially feasible in a personal care marketplace.