The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 22, 2014
Filed:
May. 04, 2009
Robert Martuza, Marblehead, MA (US);
Samuel Rabkin, Swampscott, MA (US);
Hiroaki Wakimoto, Newton, MA (US);
Ryuichi Kanai, Brookline, MA (US);
Robert Martuza, Marblehead, MA (US);
Samuel Rabkin, Swampscott, MA (US);
Hiroaki Wakimoto, Newton, MA (US);
Ryuichi Kanai, Brookline, MA (US);
The General Hospital Corporation, Boston, MA (US);
Abstract
The invention, in some aspects, relates to the selective killing of cancer stem cells by oncolytic Herpes virus mediated oncolysis. In some aspects, the invention relates to methods for treating a subject having a cancer stem cell by administering to the subject an oncolytic Herpes virus. In other aspects, the invention provides methods for evaluating the efficacy of an oncolytic Herpes virus for killing cancer stem cells.