The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 15, 2014

Filed:

Jul. 18, 2011
Applicants:

Rajinder Singh, Belmont, CA (US);

Jiaxin Yu, San Carlos, CA (US);

Hui Hong, Palo Alto, CA (US);

Sambaiah Thota, Fremont, CA (US);

Xiang Xu, Foster City, CA (US);

Ihab S. Darwish, San Carlos, CA (US);

Inventors:

Rajinder Singh, Belmont, CA (US);

Jiaxin Yu, San Carlos, CA (US);

Hui Hong, Palo Alto, CA (US);

Sambaiah Thota, Fremont, CA (US);

Xiang Xu, Foster City, CA (US);

Ihab S. Darwish, San Carlos, CA (US);

Assignee:

Rigel Pharmaceuticals, Inc., South San Francisco, CA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A01N 43/40 (2006.01); A61K 31/445 (2006.01); C07D 211/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention provides N-substituted-heterocycloalkyloxybenzamide compounds, as well as pharmaceutical compositions and methods of use. One embodiment of the invention is a compound having the structure in which R, R, R, R, T, n, w and x are as described herein. In certain embodiments of the invention, a compound of the present invention activates the AMPK pathway, and can be used to treat metabolism-related disorders and conditions.


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